A pulmonary embolism (PE) can occur when the pulmonary artery, the main blood vessel supplying the lungs, or one of its branches, becomes clogged. PE often happens when a blood clot from deep vein thrombosis (DVT), which develops in the legs, moves and lodges in the blood arteries of the lungs. Breathing difficulties, chest pain, and bloody coughing are all signs of PE. An obstruction in blood flow within the pulmonary artery affects the heart and lungs and causes symptoms of low oxygen in the rest of the body because it plays a crucial role in transporting blood to the lungs for oxygen replenishment. The magnitude of the obstruction typically determines the severity of PE. Massive PE is a common term used to describe cases where there is a major pulmonary embolism. This can result in a considerable obstruction of the pulmonary artery, which can cause serious cardiovascular distress, a dangerous drop in blood pressure, and a severe reduction in blood oxygen levels, or oxygen starvation, which can have an impact on the brain and the rest of the body. Even though a minor pulmonary embolism has less noticeable symptoms, it is nevertheless a medical emergency that, if addressed, can be fatal. Smaller blood clots typically obstruct one of the smaller branches of the pulmonary artery and may totally block a tiny pulmonary arterial, which finally results in a pulmonary infarction, or the death of some lung tissue. Within three months, a symptomatic pulmonary embolism will occur in about 50% of individuals with a symptomatic proximal DVT. DVTs are more likely to become ensnared in the lungs due to the structure of the body. Major blood vessels become lodged with large blood clots, preventing the lungs from effectively oxygenating blood. In order to see any blood clots on an X-ray, a dye is injected through a tube into the pulmonary artery during a pulmonary angiography. Before prescribing pulmonary angiography for you, your healthcare professional will carefully consider the risks and benefits because it is an invasive test that entails a chance of problems. You may need to take an oral (by mouth) anticoagulant medicine for months or even years following emergency treatment with an IV blood thinner or an injection of a clot-busting agent. Overall, PE is a rather frequent illness that, when treated promptly, has a considerably better prognosis.