Risk factors for the development of ischemic complications include invasive arterial cannulations, which are frequently used in the monitoring and treatment of hemodynamic disorders in ICU patients; the use of vasopressor drugs; coagulopathies; peripheral vascular and connective tissue diseases; hypovolemic shock; septic embolisms; medications like steroids; accompanying autonomic dysfunctions; and extremity distal ends. The cessation of cannulation, elevation, warming, anticoagulants, and/or vasodilator medications are among the treatments advised for peripheral circulatory problems. Treatment options include avoiding needless vasopressor medication use, administering peripheral blocks, and using surgical procedures, including amputation in more severe circumstances. Anticoagulant treatment is frequently used in intensive care units (ICUs) as the primary prophylactic for peripheral vascular ischemia. The prevention of peripheral ischemia in the extremities linked to edoema and compartment syndrome is shown to be a benefit of elevating the limbs. Recent studies have shown that sympathetic ultrasound-guided peripheral blocks can improve tissue perfusion, lessen ischemic discomfort, and treat vasodilation and reflex vasospasm in addition to medical and preventive care. Treatment for ischemic extremities seeks to lessen ischemia discomfort, improve blood flow, and stop limb loss brought on by ischemia. Amputation is the most serious result of peripheral circulation problems and is probably predominantly brought on by vasospastic causes. When a patient's overall health improves and vasoactive agents are stopped, the vasospasm brought on by their underlying critical illness should often go away. There is no universal agreement on the best ways to manage circulatory abnormalities in the peripheral extremities, which can be brought on by a variety of factors, including sepsis, medicines used in intensive care units, and immobility. This study has found an association between increased ICU discharge and healing of extremity ischemia caused by ultrasound-guided peripheral nerve blocks. The management of peripheral ischemia of the extremities can be accomplished with the help of peripheral block methods, despite the fact that they do not lower mortality. Additional research should be done on peripheral block methods that can be used in addition to medical treatments for treating peripheral ischemia of the extremities in intensive care units, as well as preventative approaches that go along with etiological treatment.