The pharmaceutical business is tasked with producing treatments for the numerous illnesses people contract. For many years, the processes and procedures employed to make these medications included high prices, a dearth of clinical studies, and a lack of repeatability and reproducibility. Modern technology has changed the way drug designs are created. The development of pharmacotherapy is being exponentially accelerated by in silico drug design and in silico clinical trials, which produce new medication combinations in a matter of minutes. One of the more expansive subfields of biochemistry is pharmacotherapy, or the use of medications to treat diseases rather than surgery, radiation, or other methods. As a result, the pharmacological developments for obesity, anxiety, and depression will be the main topic of this paper. Soon, doctors will be able to 3D print customised medications in any form and dosage. Drugs including cancer treatments, micromolar HIV integrase, and others are not evaluated in the conventional sense. Instead, they are inserted into virtual human and animal organ models that have been designed to imitate organ physiology. Pancreatic lipase is inhibited by the GlaxoSmithKline product orlistat, also marketed under the name Xenical. As a result of preventing the breakdown of lipids, this effectively reduces the overall number of calories digested. Blocking lipid-soluble vitamins including vitamins A, D, and K is another adverse impact. For the treatment of anxiety and depression, three major medication classes are taken into consideration. The amount of serotonin that travels via neuronal synapses is regulated by serotonergic medications like fluoxetine and Zoloft. Neuroleptics, commonly referred to as antipsychotic medications, will manage patients' behavioural responses rather than particularly target anxiety. There are still many unanswered problems about quality control and the automation of drug production, even though research is still proceeding strong and shows no signs of slowing or halting. This creates a larger problem for polypharmacy, because western doctors may prescribe an abundance of various drugs whether they are necessary or not. The long-term safety and usefulness of emerging pharmacological models, as well as adult safety profiles, are particular problems in pharmacotherapy. A technique that not every clinic and hospital follows, computerised healthcare records tracking the long-term safety of drugs, could also save many lives.